When does my prescription expire? Most NHS prescriptions expire 6 months after they are issued, although some expire after 28 days. If you're not sure if your prescription is still valid, please email email@example.com Related articles Where can I see my short-term prescriptions? When will my medication be ready to collect? Why do I need a follow-up appointment to get a repeat prescription? How prescriptions work What's the difference between a prescription and medication?